What is the relationship between CBD and metabolism

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With our cbd pollen wholesale, we are constantly looking for our balance, to ensure that the daily routine unfolds in the best possible way and without excessive tension or stress. There are some substances that are known to be able to support and restore homeostasis, or the internal balance of our organism, when necessary. We are talking about CBD, a metabolite of cannabis sativa that interfaces with our endocannabinoid system and related receptors, thus stimulating certain reactions.

This substance, which for too long has been ostracized and limited in its diffusion, is not psychoactive or psychotropic like THC (or tetrahydrocannabinol, in fact associated with the ‘high’). It is known that THC has metabolic effects, for example it can lead to an increase in hunger (which is called ‘chemical’). In this in-depth analysis we will see specifically what the relationship between CBD metabolism is.

cbd pollen wholesale: How CBD works on white fat and brown adipose tissue

Recent studies have shown how CBD influences, indirectly and in different ways, our metabolism. The effect would concern in particular what is called ‘brown fat’, or brown adipose tissue, whose main function is linked to the transformation for energy production. Unlike what happens with ‘white fat’, considered dangerous and capable of increasing the risk of diabetes and heart disease, brown fat helps burn calories and can support weight reduction.

Scholars have wondered whether CBD could function as a possible agent to treat the problem of obesity. And how? Helping in the transformation of white fat into brown fat. Among other things, in fact, CBD can help increase the activity of mitochondria and their number, improving the body’s ability to burn energy. It has also been seen that it is capable of reducing the expression of proteins that bind to the creation of new fat cells. That’s why the researchers concluded that CBD can help transform white fat into brown adipose tissue.

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cbd pollen wholesale: The endocannabinoid system is involved

Cannabis and metabolism therefore seem to be very closely linked. The endocannabinoid system, which we mentioned at the beginning of this study, is also involved in the procedure. If CBD is able to interface with the organism, it owes it precisely to the endocannabinoid system (ECS), through which it acts. It is made up of a dense network of receptors scattered throughout the body and along the nervous system, furthermore the presence of both metabolic enzymes and endocannabinoids is decisive.

The ECS is of great importance for the performance of some metabolic functions, first of all the transport of nutrients in the body and the storage of energy. The main areas of the body involved in metabolism, capable of being stimulated by the endocannabinoid system, are:
skeletal muscles,
gastrointestinal tract.
Receptors, endogenous cannabinoids and enzymes

cbd pollen wholesale: And how does the endocannabinoid system work specifically?

Through Anandamide and 2-AG, i.e. two endogenous cannabinoids that interact with the CB1 and CB2 receptors. It is precisely through the stimulation of receptors located in the brain and in the digestive tract that CBD can be useful: among other things, it supports the metabolization of foods while digestion occurs.

Excesses must always be avoided and, in this case, excessive stimulation of the endocannabinoid system and CB1 receptors can facilitate the appearance of symptoms such as hypertension, abnormal cholesterol levels and high blood sugar (connected to a condition called ‘metabolic syndrome’). Without forgetting that, in any case, the effects of the endocannabinoid system on human metabolism generally vary based on the cannabinoids used to stimulate the system. This is why it is important to distinguish CBD and THC.


Hemp and metabolism are always at the center of research and the latter to date has already managed to demonstrate how much and how CBD may be able to influence human metabolism. It is a boundless planet and partly still to be discovered, especially with regards to understanding the ECS and cannabinoids in relation to metabolism, which is why it is so important that science continues to progress in the years to come.

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